| source Berkeley (X) |
level |
department Bioengineering (X) |
This course is intended for lower division students interested in acquiring a foundation in biomedicine with topics ranging from evolutionary biology to human physiology. The emphasis is on the integration of engineering applications to biology and health. The goal is for undergraduate engineering students to gain sufficient biology and human physiology fundamentals so that they are better prepared to study specialized topics, e.g., biomechanics, imaging, computational biology, tissue engineering, biomonitoring, drug development, robotics, and other topics covered by upper division and graduate courses in UC Berkeley departments of Molecular and Cell Biology, Integrative Biology, Bioengineering, Electrical Engineering and Computer Science, Mechanical Engineering, and courses in the UC San Francisco Division of Bioengineering. The specific lecture topics and exercises will include the key aspects of genomics and proteomics as well as topics on plant and animal evolution, stem cell biomedicine, and tissue regeneration and replacement. Medical physiology topics include relevant engineering aspects of human brain, heart, musculoskeletal, and other systems.
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This course is intended to introduce students to a variety of fields that fall under the biotechnology umbrella. In general, these fields include medical, microbial, agricultural, animal, and forensic biotechnology. Students in this course will learn the types of biotechnology projects currently being worked on, as well as the techniques and assays used within these projects.
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This course is intended to introduce students to a variety of laboratory techniques that are used in current day biotechnology projects. During this course, students will get hands-on molecular and cellular biotechnology experience working with E. coli, Yeast, Human and Mouse Cell Lines, DNA, RNA, and proteins. This is a bioengineering course; the focus of these exercises will be on the critical understanding of biological, biochemical, or physical mechanisms, and theories of different experiemental methods, techniques, and instrumentation used. Second, students leaving this class should understand how to address a critical biological question and design experiments in a quantitative manner.
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This introductory seminar is designed to give freshmen and sophomores a glimpse of a broad selection of bioengineering research that is currently underway at Berkeley and UCSF. The goal is to help students gain a feeling for the breadth of interesting problems in bioengineering and also the variety of ways that engineering principles can be applied to biological and medical problems. A series of one-hour seminars will be presented by researchers, professors, and doctors on their particular research areas.
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This introductory seminar is designed to give freshmen and sophomores an opportunity to explore specialties related to engineering in the pharmaceutical/biotech field. A series of one-hour seminars will be presented by industry professionals, professors, and researchers. Topics may include biotechnology and pharmaceutical manufacturing; process and control engineering; drug inspection process; research and development; compliance and validation; construction process for a GMP facility; project management; and engineered solutions to environmental challenges. This course is of interest to students in all areas of engineering and biology, including industrial engineering and manufacturing, chemical engineering, and bioengineering.
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The goal of this semester course is to present the issues of professional conduct in the practice of engineering, research, publication, public and private disclosures, and in managing professional and financial conflicts. The method is through historical didactic presentations, case studies, presentations of methods for problem solving in ethical matters, and classroom debates on contemporary ethical issues. The faculty will be drawn from national experts and faculty from religious studies, journalism, and law from the UC Berkeley campus.
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This course teaches the fundamental principles underlying modern instrumentation used in biology and medicine. Organized around three classes of instruments--bioelectronics, optical microscopy, and medical imaging--the course takes an integrative approach to measurement theory and practice by presenting and analyzing example instruments currently used for biological and medical research. For each instrument, students will learn the fundamentals of operation, methods of control, mechanisms of contrast, devices for detection, and methods for signal processing and error estimation. Current biological questions and medical problems investigated with each type of instrument will be discussed.
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This course introduces, develops, and applies scaling laws and the methods of continuum mechanics to tissue-level biomechanical phenomena. It is intended for upper level undergraduate students who have been exposed to vectors and tensors, differential equations, and undergraduate courses in either fluids or transport, and molecular biology. Topics include biosolid and biofluid mechanics; elastic (time-independent), viscoelastic, and poroelastic (time-dependent) behavior of tissues; continuum and microstructural models; constitutive laws; material properties of tissues; experimental methods--macroscopic rheology.
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The transport of mass, momentum, and energy are critical to the function of living systems and the design of medical devices. Biological transport phenomena are present at a wide range of length scales: molecular, cellular, organ (whole and by functional unit), and organism. This course develops and applies scaling laws and the methods of continuum mechanics to biological transport phenomena over a range of length and time scales. The course is intended for undergraduate students who have taken a course in differential equations and an introductory course in physics. Students should be familiar with basic biology; an understanding of physiology is useful, but not assumed.
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This course introduces the basic principles of thermodynamics and their application to a variety of biological processes and systems. Some coverage of conventional engineering applications is also included. Also listed as Mechanical Engineering C105B.
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This course introduces students to the physiology of human organ systems, with an emphasis on quantitative problem solving, engineering-style modeling, and applications to clinical medicine. The course will begin with a review of basic principles of cellular physiology, including membrane transport and electrophysiology, and then take a system-by-system approach to the physiology of various organ systems, including the cardiovascular, pulmonary, renal, and endocrine systems. Throughout, the course will feature extensive discussions of clinical conditions associated with dysfunction in specific physiological processes as well as the role of medical devices and prostheses. This course is geared towards upper-division bioengineering students who wish to solidify their foundation in physiology, especially in preparation for a career in clinical medicine or the biomedical device industry.
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This course is intended for upper level engineering undergraduate students interested in the development of novel functional proteins and peptide motifs and characterization of their physical and biological properties using various instrumentation tools in quantitative manners.
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This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular levels. It is intended for senior undergraduate students who have been exposed to differential equations, mechanics, and certain aspects of modern biology.
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This course will teach the main concepts and current views on key attributes of embryonic stem cells (ESC), will introduce theory of their function in embryonic development, methods of ESC derivation, propagation, and characterization, and will discuss currently developing stem cell technologies.
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The structural and functional characteristics of tissues are altered by cells in response to culture conditions, loading, injury, and various other factors. A contemporary understanding of the form, function, and longevity of tissues includes knowledge of tissue microstructure, composition of matrix, and cell function. Students will be introduced to molecular biology techniques as applied to cells and tissues including immunofluorescence, image analysis, protein quantification, gene expression, and cell culture.
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The goal of tissue engineering is to fabricate substitutes to restore tissue structure and functions. Understanding cell function in response to environmental cues will help us to establish design criteria and develop engineering tools for tissue fabrication. This course will introduce the basic concepts and approaches in the field, and train students to design and engineer biological substitutes. Lectures will be based on the textbook, the reference books and recent literature. Discussion sections will include the discussion of current literature and issues related to course content, homework, exams, and projects. Homework includes quantitative analysis, essay questions, and literature research. There will be a midterm exam, final exam, and a design project (presentation and paper). The final project will be a group project (three to four students) or independent project (required for graduate students). The topic will be chosen by each group and approved by instructor/GSIs.
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This course covers the structure and mechanical functions of load bearing tissues and their replacements. Natural and synthetic load-bearing biomaterials for clinical applications are reviewed. Biocompatibility of biomaterials and host response to structural implants are examined. Quantitative treatment of biomechanical issues and constitutive relationships of tissues are covered in order to design biomaterial replacements for structural function. Material selection for load bearing applications including reconstructive surgery, orthopedics, dentistry, and cardiology are addressed. Mechanical design for longevity including topics of fatigue, wear, and fracture are reviewed. Case studies that examine failures of devices are presented. This course includes a teaching/design laboratory component that involves design analysis of medical devices and outreach teaching to the public community. Several problem-based projects are utilized throughout the semester for design analysis. In addition to technical content, this course involves rigorous technical writing assignments, oral communication skill development and teamwork. Also listed as Mechanical Engineering C117.
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This course is intended to give students the opportunity to expand their knowledge of topics related to biomedical materials selection and design. Structure-property relationships of biomedical materials and their interaction with biological systems will be addressed. Applications of the concepts developed include blood-materials compatibility, biomimetic materials, hard and soft tissue-materials interactions, drug delivery, tissue engineering, and biotechnology. Also listed as Materials Science and Engineering C118.
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Students will learn the application of engineering concepts including statics, dynamics, optimization theory, composite beam theory, beam-on-elastic foundation theory, Hertz contact theory and materials behavior. Topics will include forces and moments acting on human joints; composition and mechanical behavior of orthopedic biomaterials; design/analysis of artificial joint, spine, and fracture fixation prostheses; musculoskeletal tissues including bone, cartilage, tendon, ligament, and muscle; osteoporosis and fracture-risk predication of bones; and bone adaptation. Students will be challenged in a MATLAB-based project to integrate the course material in an attempt to gain insight into contemporary design/analysis/problems. Also listed as Mechanical Engineering C176.
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Biophysical and chemical principles of biomedical microelectromechanical systems (bioMEMS) for the measurement of biological phenomena and clinical applications. Micro- and nano-scale devices for the manipulation of cells and biomolecules. Topics include solid-state transducers, optical transducers, electrochemical transducers, biomedical microelectronics, microfluidics, and hybrid integration of microfabrication technology.
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Hands-on project experience in applying microfabrication techniques to problems in biotechnology using the latest micro- and nano-technological tools. Experimental design and analysis of micro- and nano-scale device interfaces. Students will give poster sessions and oral presentations on their results.
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An introduction to the kinematics, dynamics, and control of robot manipulators, robotic vision, and sensing. The course covers forward and inverse kinematics of serial chain manipulators, the manipulator Jacobian, force relations, dynamics, and control. It presents elementary principles on proximity, tactile, and force sensing, vision sensors, camera calibration, stereo construction, and motion detection. The course concludes with current applications of robotics in active perception, medical robotics, and other areas. Also listed as Electrical Engineering C125.
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Topics include computational approaches and techniques to gene structure and finding, sequence alignment using dynamic programming, protein folding and structure prediction, protein-drug interactions, genetic and biochemical pathways and networks, and microarray analysis. Various case studies in these areas are reviewed and web-based computational biology tools will be used by students. Computational biology research connections to biotechnology will be explored.
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This course is aimed at graduate and advanced undergraduate students from the (bio) engineering and chemo-physical sciences interested in a research-oriented introduction to current topics in systems biology. Focusing mainly on two well studied microbiological model systems--the chemotaxis network and Lambda bacteriophage infection--the class systematically introduces key concepts and techniques for biological network deduction, modelling, analysis, evolution, and synthetic network design. Students analyze the impact of approaches from the quantitative sciences--such as deterministic modelling, stochastic processes, statistics, non-linear dynamics, control theory, information theory, graph theory, etc.--on understanding biological processes, including (stochastic) gene regulation, signalling, network evolution, and synthetic network design. The course aims to identify unsolved problems and discusses possible novel approaches while encouraging students to develop ideas to explore new directions in their own research.
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Introduction to laboratory and field study of the biomechanics of animals and plants using fundamental biomechanical techniques and equipment. Course has a series of rotations involving students in experiments demonstrating how solid and fluid mechanics can be used to discover the way in which diverse organisms move and interact with their physical environment. The laboratories emphasize sampling methodology, experimental design, and statistical interpretation of results. Latter third of course devoted to independent research projects. Written reports and class presentation of project results are required. Also listed as Electrical Engineering C145O, Mechanical Engineering C177L, and Integrative Biology C135L.
Score: 9.384323 Details | Listing | Web page