| source Caltech (X) |
level |
department Biology (X) |
This course introduces nonbiologists to recent advances in our understanding of how HIV and other viruses infect and cause damage to their hosts. Because understanding and treating HIV infection involves a basic knowledge of cell and molecular biology, virology, and immunology, the course will cover fundamental concepts in these areas from a quantitative, molecular, chemical, and biophysical perspective. Instructors: Bjorkman, Phillips.
Score: 8.04859 Details | Listing | Web page
Current research in biology will be discussed, on the basis of reading assigned in advance of the discussions, with members of the divisional faculty. Graded pass/fail. Instructor: Elowitz.
Score: 8.04859 Details | Listing | Web page
This course and its sequel, Bi 9, cover biology at the cellular level. After introducing basic concepts necessary for understanding biological systems at the molecular level, Bi 8 emphasizes cellular processes involved in the organization and expression of genetic information, including what is commonly called molecular biology, and introduces topics in developmental biology and immunology. Graded pass/fail. Instructor: Stathopoulos.
Score: 8.04859 Details | Listing | Web page
Continues coverage of biology at the cellular level, begun in Bi 8. Topics: cytoplasmic structure, membrane structure and function, cell motility, and cell-cell recognition. Emphasis on both the ultrastructural and biochemical approaches to these topics. Instructors: Rothenberg, staff.
Score: 8.04859 Details | Listing | Web page
Introduction to basic methods in cell and molecular biological research, including polymerase chain reaction, molecular cloning, expression and purification of recombinant fusion proteins in bacteria, enzymology, and gel electrophoresis of proteins and nucleic acids. Instructor: Deshaies.
Score: 8.04859 Details | Listing | Web page
Special problems involving laboratory research in biology; to be arranged with instructors before registration. Graded pass/fail. Instructor: Staff.
Score: 8.04859 Details | Listing | Web page
Study and discussion of special problems in biology, usually involving regular tutorial sessions with instructors. To be arranged through the instructor before registration. Graded pass/fail.
Score: 8.04859 Details | Listing | Web page
This course offers instruction and practice in writing and speaking relevant to professional biologists working in research, teaching, and/or medical careers. Students may write a paper for a scientific journal, based on their previous research and mentored by a faculty member. Alternatively, students may produce a variety of brief writing assignments with a range of audiences and purposes. Oral presentations will be based on writing produced in the course, with feedback from instructors and peers.
Score: 8.04859 Details | Listing | Web page
Intended to extend opportunities for research provided by Bi 22 into a coherent individual research project, carried out under the supervision of a member of the biology faculty. Normally involves three or more consecutive terms of work in the junior and senior years. The student will formulate a research problem based in part on work already carried out, evaluate previously published work in the field, and present new results in a thesis format. First two terms graded pass/fail; final term graded by letter on the basis of the completed thesis. Instructor: Lester.
Score: 8.04859 Details | Listing | Web page
For course description, see Computation and Neural Systems.
Score: 8.04859 Details | Listing | Web page
For course description, see Physics.
Score: 8.04859 Details | Listing | Web page
Lectures and recitation introducing the molecular basis of life processes, with emphasis on the structure and function of proteins. Topics will include the derivation of protein structure from the information inherent in a genome, biological catalysis, the intermediary metabolism that provides energy to an organism, and the use of DNA manipulations, cloning, and expression of proteins in foreign hosts to study protein structure and function. Instructors: Richards, Campbell.
Score: 8.04859 Details | Listing | Web page
Lectures and recitation on the molecular basis of biological structure and function. Emphasizes the storage, transmission, and expression of genetic information in cells. Specific topics include DNA replication, recombination, repair and mutagenesis, transcription, RNA processing, and protein synthesis. Instructors: Campbell, Parker.
Score: 8.04859 Details | Listing | Web page
Lectures and recitation on the biochemistry of basic cellular processes in the cytosol and at the cell surface, with emphasis on signal transduction, membrane trafficking, and control of cell division. Specific topics include cell-cell signaling, control of gene expression by cell surface molecules, tumorigenesis, endocytosis, exocytosis, viral entry, and cell cycle regulation. Instructors: Chan, Shan.
Score: 8.04859 Details | Listing | Web page
The course will cover the molecular and cellular mechanisms that mediate recognition and response in the mammalian immune system. Topics include cellular and humoral immunity, the structural basis of immune recognition, antigen presentation and processing, developmental regulation of gene rearrangement, biochemistry of lymphocyte activation, lymphokines and the regulation of cellular responses, T and B cell development, and mechanisms of tolerance. Instructor: Mazmanian.
Score: 8.04859 Details | Listing | Web page
Introduction to the chemistry and biology of viruses. Emphasis on replication strategies of animal viruses, with consideration also given to epidemiology of viruses, nature and control of virus diseases, evolution of viruses, and some aspects of bacterial and plant virus replication. Given in alternate years; not offered 2008–09.
Score: 8.04859 Details | Listing | Web page
For course description, see Computation and Neural Systems.
Score: 8.04859 Details | Listing | Web page
Lecture and discussion course covering basic principles of genetics. Instructor: Hay.
Score: 8.04859 Details | Listing | Web page
Laboratory exercises illustrating the principles of genetics, with emphasis on Mendelian inheritance in multicellular eukaryotes, including
Score: 8.04859 Details | Listing | Web page
Topics to be covered include protein trafficking to dendrites and axons, local synaptic protein synthesis, neuronal cytoskeletal dynamics, protein degradation, calcium signaling, and signal transduction cascades in synapses. Instructors: Schuman, Zinn.
Score: 8.04859 Details | Listing | Web page
For course description, see Computation and Neural Systems.
Score: 8.04859 Details | Listing | Web page
Structural and functional aspects of nucleic acids and proteins, including hybridization; electrophoretic behavior of nucleic acids; principles and energetics of folding of polypeptide chains in proteins; allostery and cooperativity in protein action; enzyme kinetics and mechanisms; and methods of structure determination, such as X-ray diffraction and magnetic resonance. Structure and function of metalloenzymes. Instructors: Barton, Beauchamp.
Score: 8.04859 Details | Listing | Web page
Fundamental issues in emotion research at multiple levels of experimental analysis, and in species ranging from humans to mice to flies. Psychological theories and data from studies in humans will be presented to clarify the relationship between emotional behavior, affect, feelings, and moods, which in turn will form the basis for exploring whether and how different animal models can be used to investigate the neural circuit and molecular bases of emotion. Can genetically tractable model organisms such as flies show “emotional behavior,” or have “feelings”? What have we learned from animal models about the neural circuit and genetic bases of emotional behavior, and how does it relate to what we know from human studies? Disorders of emotion will also be discussed, including affective disorders in humans, and their potential animal models. Instructors: Anderson, Adolphs.
Score: 8.04859 Details | Listing | Web page
For course description, see Social Science.
Score: 8.04859 Details | Listing | Web page
General principles of the function and organization of nervous systems, providing both an overview of the subject and a foundation for advanced courses. Topics include the physical and chemical bases for action potentials, synaptic transmission, and sensory transduction; anatomy; development; sensory and motor pathways; memory and learning at the molecular, cellular, and systems level; and the neuroscience of brain diseases. Instructors: Adolphs, Kennedy, Lester.
Score: 8.04859 Details | Listing | Web page