| source UCLA (X) |
level |
department Biomedical Engineering (X) |
Seminar, one hour. Discussion of and critical thinking about topics of current intellectual importance, taught by faculty members in their areas of expertise and illuminating many paths of discovery at UCLA. P/NP grading.
Score: 6.8854284 Details | Listing | Web page
Tutorial (supervised research or other scholarly work), three hours per week per unit. Entry-level research for lower division students under guidance of faculty mentor. Students must be in good academic standing and enrolled in minimum of 12 units (excluding this course). Individual contract required; consult Undergraduate Research Center. May be repeated. P/NP grading.
Score: 6.8854284 Details | Listing | Web page
Lecture, three hours; laboratory, three hours; outside study, six hours. Designed for physical sciences, life sciences, and engineering students. Introduction to wide scope of biomedical engineering via treatment of selected important individual topics by small team of specialists. Concurrently scheduled with course C201. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Physiological Science CM102.) Lecture, three hours; laboratory, two hours. Preparation: human molecular biology, biochemistry, and cell biology. Not open for credit to Physiological Science majors. Broad overview of basic biological activities and organization of human body in system (organ/tissue) to system basis, with particular emphasis on molecular basis. Modeling/simulation of functional aspect of biological system included. Actual demonstration of biomedical instruments, as well as visits to biomedical facilities. Concurrently scheduled with course CM202. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Physiological Science CM103.) Lecture, three hours; laboratory, two hours. Preparation: human molecular biology, biochemistry, and cell biology. Not open for credit to Physiological Science majors. Molecular-level understanding of human anatomy and physiology in selected organ systems (digestive, skin, musculoskeletal, endocrine, immune, urinary, reproductive). System-specific modeling/simulations (immune regulation, wound healing, muscle mechanics and energetics, acid-base balance, excretion). Functional basis of biomedical instrumentation (dialysis, artificial skin, pathogen detectors, ultrasound, birth-control drug delivery). Concurrently scheduled with course CM203. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Bioengineering M104.) Lecture, three hours; discussion, two hours; outside study, seven hours. Requisites: Chemistry 20A, 20B, 30A, Life Sciences 2, 3. To understand biological materials and design synthetic replacements, it is imperative to understand their physical chemistry. Biomacromolecules such as protein or DNA can be analyzed and characterized by applying fundamentals of polymer physical chemistry. Investigation of polymer structure and conformation, bulk and solution thermodynamics and phase behavior, polymer networks, and viscoelasticity. Application of engineering principles to problems involving biomacromolecules such as protein conformation, solvation of charged species, and separation and characterization of biomacromolecules. Concurrently scheduled with course C204. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Bioengineering M105.) Lecture, four hours; discussion, one hour; outside study, seven hours. Enforced requisites: Chemistry 20A, 20B, 20L. Highly recommended: one organic chemistry course. Bioconjugate chemistry is science of coupling biomolecules for wide range of applications. Oligonucleotides may be coupled to one surface in gene chip, or one protein may be coupled to one polymer to enhance its stability in serum. Wide variety of bioconjugates are used in delivery of pharmaceuticals, in sensors, in medial diagnostics, and in tissue engineering. Basic concepts of chemical ligation, including choice and design of conjugate linkers depending on type of biomolecule and desired application, such as degradable versus nondegradable linkers. Presentation and discussion of design and synthesis of synthetic bioconjugates for some sample applications. Concurrently scheduled with course C205. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Bioengineering M106.) Lecture, three hours; discussion, one hour; outside study, eight hours. Requisites: Chemistry 20B, Life Sciences 2, 3, 4, Mathematics 33B, Physics 1C, 4AL, 4BL. Coverage in depth of physical processes associated with biological membranes and channel proteins, with specific emphasis on electrophysiology. Basic physical principles governing electrostatics in dielectric media, building on complexity to ultimately address action potentials and signal propagation in nerves. Topics include Nernst/Planck and Poisson/Boltzmann equations, Nernst potential, Donnan equilibrium, GHK equations, energy barriers in ion channels, cable equation, action potentials, Hodgkin/Huxley equations, impulse propagation, axon geometry and conduction, dendritic integration. Concurrently scheduled with course C206. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Bioengineering M131.) Lecture, four hours; discussion, one hour; outside study, seven hours. Requisites: Bioengineering 100, 120, Life Sciences 2, 3, Physics 1A, 1B, 1C. Analysis of sensors based on measurements of fluctuating ionic conductance through artificial or protein nanopores. Physics of pore conductance. Applications to single molecule detection and DNA sequencing. Review of current literature and technological applications. History and instrumentation of resistive pulse sensing, theory and instrumentation of electrical measurements in electrolytes, nanopore fabrication, ionic conductance through pores and GHK equation, patch clamp and single channel measurements and instrumentation, noise issues, protein engineering, molecular sensing, DNA sequencing, membrane engineering, and future directions of field. Concurrently scheduled with course C231. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Mechanical and Aerospace Engineering CM140.) Lecture, four hours; discussion, two hours; outside study, six hours. Requisites: Mechanical and Aerospace Engineering 101, 102, 156A. Introduction to mechanical functions of human body; skeletal adaptations to optimize load transfer, mobility, and function. Dynamics and kinematics. Fluid mechanics applications. Heat and mass transfer. Power generation. Laboratory simulations and tests. Concurrently scheduled with course CM240. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Chemical Engineering CM145.) Lecture, four hours; discussion, one hour; outside study, eight hours. Selected topics in molecular biology that form foundation of biotechnology and biomedical industry today. Topics include recombinant DNA technology, molecular research tools, manipulation of gene expression, directed mutagenesis and protein engineering, DNA-based diagnostics and DNA microarrays, antibody and protein-based diagnostics, genomics and bioinformatics, isolation of human genes, gene therapy, and tissue engineering. Concurrently scheduled with course CM245. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Formerly numbered M150.) (Same as Electrical Engineering CM150 and Mechanical and Aerospace Engineering CM180.) Lecture, four hours; discussion, one hour; outside study, seven hours. Requisites: Chemistry 20A, 20L, Physics 1A, 1B, 1C, 4AL, 4BL. Corequisite: course CM150L. Introduction to micromachining technologies and microelectromechanical systems (MEMS). Methods of micromachining and how these methods can be used to produce variety of MEMS, including microstructures, microsensors, and microactuators. Students design microfabrication processes capable of achieving desired MEMS device. Concurrently scheduled with course CM250A. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Formerly numbered M150L.) (Same as Electrical Engineering CM150L and Mechanical and Aerospace Engineering CM180L.) Lecture, one hour; laboratory, four hours; outside study, one hour. Requisites: Chemistry 20A, 20L, Physics 1A, 1B, 1C, 4AL, 4BL. Corequisite: course CM150. Hands-on introduction to micromachining technologies and microelectromechanical systems (MEMS) laboratory. Methods of micromachining and how these methods can be used to produce variety of MEMS, including microstructures, microsensors, and microactuators. Students go through process of fabricating MEMS device. Concurrently scheduled with course CM250L. Letter grading.
Score: 6.8854284 Details | Listing | Web page
Lecture, three hours; outside study, nine hours. Requisites: Electrical Engineering 172, 175, Life Sciences 3, Physics 17. Corequisite: course C170L. Introduction to therapeutic and diagnostic use of energy delivery devices in medical and dental applications, with emphasis on understanding fundamental mechanisms underlying various types of energy-tissue interactions. Concurrently scheduled with course C270. Letter grading.
Score: 6.8854284 Details | Listing | Web page
Laboratory, four hours; outside study, two hours. Corequisite: course C170. Introduction to simulation and experimental techniques used in studying laser-tissue interactions. Topics include computer simulations of light propagation in tissue, measuring absorption spectra of tissue/tissue phantoms, making tissue phantoms, determination of optical properties of different tissues, techniques of temperature distribution measurements. Concurrently scheduled with course C270L. Letter grading.
Score: 6.8854284 Details | Listing | Web page
Lecture, four hours; outside study, eight hours. Requisite: course C170. Designed for physical sciences, life sciences, and engineering majors. Introduction to optical spectroscopy principles, design of spectroscopic measurement devices, optical properties of tissues, and fluorescence spectroscopy biologic media. Concurrently scheduled with course C271. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Bioengineering M172.) Lecture, three hours; discussion, two hours; outside study, seven hours. Requisites: Chemistry 30B, Life Sciences 2, 3, Mathematics 32A. Introduction to design principles and engineering concepts used in design and manufacture of tools for minimally invasive surgery. Coverage of FDA regulatory policy and surgical procedures. Topics include optical devices, endoscopes and laparoscopes, biopsy devices, laparoscopic tools, cardiovascular and interventional radiology devices, orthopedic instrumentation, and integration of devices with therapy. Examination of complex process of tool design, fabrication, testing, and validation. Preparation of drawings and consideration of development of new and novel devices. Concurrently scheduled with course C272. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Materials Science CM180.) Lecture, three hours; discussion, two hours; outside study, seven hours. Requisites: Chemistry 20A, 20B, and 20L, or Materials Science 104. Engineering materials used in medicine and dentistry for repair and/or restoration of damaged natural tissues. Topics include relationships between material properties, suitability to task, surface chemistry, processing and treatment methods, and biocompatibility. Concurrently scheduled with course CM280. Letter grading.
Score: 6.8854284 Details | Listing | Web page
Lecture, three hours; outside study, nine hours. Requisite: course CM180. In-depth exploration of host cellular response to biomaterials: vascular response, interface, and clotting, biocompatibility, animal models, inflammation, infection, extracellular matrix, cell adhesion, and role of mechanical forces. Concurrently scheduled with course C281. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Bioengineering M183.) Lecture, three hours; discussion, two hours; outside study, seven hours. Requisites: Chemistry 20A, 20B, 20L. New therapeutics require comprehensive understanding of modern biology, physiology, biomaterials, and engineering. Targeted delivery of genes and drugs and their controlled release are important in treatment of challenging diseases and relevant to tissue engineering and regenerative medicine. Drug pharmacodynamics and clinical pharmacokinetics. Application of engineering principles (diffusion, transport, kinetics) to problems in drug formulation and delivery to establish rationale for design and development of novel drug delivery systems that can provide spatial and temporal control of drug release. Introduction to biomaterials with specialized structural and interfacial properties. Exploration of both chemistry of materials and physical presentation of devices and compounds used in delivery and release. Concurrently scheduled with course C283. Letter grading.
Score: 6.8854284 Details | Listing | Web page
Lecture, three hours; discussion, one hour; outside study, eight hours. Requisites: course CM102 or CM202, Chemistry 20A, 20B, 20L. Tissue engineering applies principles of biology and physical sciences with engineering approach to regenerate tissues and organs. Guiding principles for proper selection of three basic components for tissue engineering: cells, scaffolds, and molecular signals. Concurrently scheduled with course C285. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Same as Computational and Systems Biology M186A and Computer Science M186A.) Lecture, two hours; outside study, four hours. Requisites: Computer Science 31 (or Program in Computing 10A), Mathematics 31A, 31B. Survey course designed to introduce students to computational and systems modeling and computing in biology and medicine, providing flavor, culture, and cutting-edge contributions of burgeoning computational multidisciplinary biosciences and aiming for more informed basis for joining them. Integrative introduction with emphasis on ongoing computational and systems biology research at UCLA in systems biology, bioinformatics, genomics, neuroengineering, tissue bioengineering, systems biology software, knowledge systems, biosystem simulation, and/or other computational and systems biology/biomedical engineering areas. P/NP grading.
Score: 6.8854284 Details | Listing | Web page
(Formerly numbered M186B.) (Same as Computational and Systems Biology M186B and Computer Science CM186B.) Lecture, four hours; laboratory, three hours; outside study, eight hours. Corequisite: Electrical Engineering 102. Dynamic biosystems modeling and computer simulation methods for studying biological/biomedical processes and systems at multiple levels of organization. Control system, multicompartmental, predator-prey, pharmacokinetic (PK), pharmacodynamic (PD), and other structural modeling methods applied to life sciences problems at molecular, cellular (biochemical pathways/networks), organ, and organismic levels. Both theory- and data-driven modeling, with focus on translating biomodeling goals and data into mathematics models and implementing them for simulation and analysis. Basics of numerical simulation algorithms, with modeling software exercises in class and PC laboratory assignments. Concurrently scheduled with course CM286B. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Formerly numbered CM186L.) (Same as Computational and Systems Biology M186C and Computer Science CM186C.) Lecture, one hour; discussion, two hours; laboratory, one hour; outside study, eight hours. Requisite: course CM186B. Closely directed, interactive, and real research experience in active quantitative systems biology research laboratory. Direction on how to focus on topics of current interest in scientific community, appropriate to student interests and capabilities. Critiques of oral presentations and written progress reports explain how to proceed with search for research results. Major emphasis on effective research reporting, both oral and written. Concurrently scheduled with course CM286C. Letter grading.
Score: 6.8854284 Details | Listing | Web page
(Formerly numbered CM186L.) (Same as Computational and Systems Biology M186C and Computer Science CM186C.) Lecture, one hour; discussion, two hours; laboratory, one hour; outside study, eight hours. Requisite: course CM186B. Closely directed, interactive, and real research experience in active quantitative systems biology research laboratory. Direction on how to focus on topics of current interest in scientific community, appropriate to student interests and capabilities. Critiques of oral presentations and written progress reports explain how to proceed with search for research results. Major emphasis on effective research reporting, both oral and written. Concurrently scheduled with course CM286C. Letter grading.
Score: 6.8854284 Details | Listing | Web page