| source UC Santa Barbara (X) |
level |
department Biomolecular Science and Engineering (X) |
Freshman seminar. Exploration of the biochemical basis of selected characteristics of living systems. Biological order, specificity and continuity will be considered in terms of molecular descriptions of cells and cellular processes, including metabolism, growth and development.
Score: 10.681405 Details | Listing | Web page
Structure and function of proteins and other macromolecules; enzymatic catalysis.
Score: 10.681405 Details | Listing | Web page
Metabolism; metabolic regulatory mechanisms and bioenergetics.
Score: 10.681405 Details | Listing | Web page
Structure and function of nucleic acids; biochemistry of DNA replication, RNA transcription, and translation.
Score: 10.681405 Details | Listing | Web page
Isolation and structural analysis of biomolecules; hydrodynamics, spectroscopy, diffraction, scattering.
Score: 10.681405 Details | Listing | Web page
Lectures by UCSB faculty from various departments focused on their current research in a variety of biomedical disciplines.
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Special topics of current importance in biochemistry and molecular biology.Course content will vary. Information may be obtained in the program office.
Score: 10.681405 Details | Listing | Web page
Research internship in biotechnology or pharmaceutical company laboratory. Placement negotiated on individual basis.
Score: 10.681405 Details | Listing | Web page
Individual courses one hour every two weeks. Special readings designed to broaden the outlook of students and to knit into a cohesive whole the basic principles underlying the major disciplines of biochemistry and molecular biology.
Score: 10.681405 Details | Listing | Web page
Hours and credit arranged with any member of the staff. Laboratory.
Score: 10.681405 Details | Listing | Web page
Traces the physical interactions by which sequence-specific polypeptides attain a unique, functional native state. Fold design, fold prediction, and protein folding kinetics are also discussed.
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Primary, seondary, and higher-order structures of DNA and RNA, thermodynamic stability and folding, protein-nucleic acid interactions, ribozymes, applications to gene regulation, RNA world evolution.
Score: 10.681405 Details | Listing | Web page
Lipid diversity, lipid aggregates, dynamics and phase behavior of lipid aggregates, permeabilities of model and cellular bilayers, manipulation and quantification of ionic and pH gradients, related special topics in physiology such as the mechanisms of anesthesia.
Score: 10.681405 Details | Listing | Web page
Fundamentals of natural and artificial biomaterials and biosurfaces with emphasis on molecular level structure and function and the interactions of biomaterials and surfaces with the body. Design issues of grafts and biopolymers. Basic biological and biochemical systems reviewed for nonbiologists.
Score: 10.681405 Details | Listing | Web page
Rational design of protein structure, activity, and stability. Current methods and applications of protein engineering including protein evolution, unnatural amino acids, and combinatorial methods.
Score: 10.681405 Details | Listing | Web page
Structure/function relationships in interesting macromolecules isolated from marine organisms. Focus is on well-characterized pathways from horseshoe crabs, abalones, mussels, and fish as well as others.
Score: 10.681405 Details | Listing | Web page
A practical approach to purifying and working with proteins in the laboratory. Emphasis is on techniques (mainly qualitative) with a focus on modern methods used in the research literature. Students will have an intuitive sense of protein purification, manipulations, and analysis, and should be able to critically read the primary literature upon successful completion of the course.
Score: 10.681405 Details | Listing | Web page
A presentation of traditional and state-of-the-art approaches for characterizing the primary structure of proteins and polysaccharides. Techniques to be included are amino acid analysis, mass spectrometry, gas-phase sequencing, capillary electrophoresis, and covalent modification chemistry.
Score: 10.681405 Details | Listing | Web page
Chemical mechanisms of enzyme catalysis. Enzyme models and non-classical enzymes. Theory, experimental design, and data analysis.
Score: 10.681405 Details | Listing | Web page
An intensive laboratory course for physical science and engineering students providing background knowledge and laboratory experience in standard molecular biology and protein purification techniques, as well as techniques for characterizing purified proteins.
Score: 10.681405 Details | Listing | Web page
Course focuses on biopolymers as structurally dynamic systems. Exploration of the relationship between biopolymer sequence, the structure that these sequences encode and the kinetic mechanisms by which this structure is achieved.
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An overview of those parts of chemical thermodynamics relevant to the study of biomolecules and biological systems. Topics include fundamental biopolymer structure formation.
Score: 10.681405 Details | Listing | Web page
Introduction to the application of spectroscopic techniques to biological systems, including UV - vis, IR, CD, fluorescence, NMR and ESR.
Score: 10.681405 Details | Listing | Web page
Single-crystal macromolecular crystallography methods; crystal growth, geometric and physical basis of diffraction, approaches to phasing and refinement. Xray and neutron solution scattering.
Score: 10.681405 Details | Listing | Web page
Electrostatics of highly charged sufaces in contact with a polar solvent with application to biopolymers (e.g., DNA, f-actin).
Score: 10.681405 Details | Listing | Web page