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Total results: 61

University of Auckland - Human Mind and Body Relationships

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle Physiology and Pathophysiology of the Brain

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field. The relationship between the structure and function of the nervous system in health and disease. Topics include organisational principles of the CNS, imaging of the human brain, synaptic function in health and disease, selected topics in pathophysiology of motor and sensory systems (including vision and auditory function), brain ischemia and sleep/sleep disorders. The topics are covered at an advanced level with emphasis on current advances in the fields.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle Physiology and Pathophysiology of the Brain Cardiovascular Biology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field. The relationship between the structure and function of the nervous system in health and disease. Topics include organisational principles of the CNS, imaging of the human brain, synaptic function in health and disease, selected topics in pathophysiology of motor and sensory systems (including vision and auditory function), brain ischemia and sleep/sleep disorders. The topics are covered at an advanced level with emphasis on current advances in the fields. An advanced treatment of the human cardiovascular system that provides an integrated framework for understanding the structure, function and regulation of the heart and circulation, and their modification by drugs. Topics include: the energetics and mechanics of the heart, the regulation of heart rhythm and the control of blood pressure and the regulation of flow through the microcirculation. The course is illustrated using examples drawn from current research in the field and from representative disease states.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle Physiology and Pathophysiology of the Brain Cardiovascular Biology Endocrinology of Growth and Metabolism

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field. The relationship between the structure and function of the nervous system in health and disease. Topics include organisational principles of the CNS, imaging of the human brain, synaptic function in health and disease, selected topics in pathophysiology of motor and sensory systems (including vision and auditory function), brain ischemia and sleep/sleep disorders. The topics are covered at an advanced level with emphasis on current advances in the fields. An advanced treatment of the human cardiovascular system that provides an integrated framework for understanding the structure, function and regulation of the heart and circulation, and their modification by drugs. Topics include: the energetics and mechanics of the heart, the regulation of heart rhythm and the control of blood pressure and the regulation of flow through the microcirculation. The course is illustrated using examples drawn from current research in the field and from representative disease states. An introduction to the mechanism controlling the production of hormones and how these achieve their effects in regulating body function. The course focuses in particular on the hormone systems controlling growth and metabolism and contrasts the differences between fetal and adult life. It also highlights how defects in endocrine systems are associated with conditions such as obesity and diabetes.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle Physiology and Pathophysiology of the Brain Cardiovascular Biology Endocrinology of Growth and Metabolism Reproductive Biology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field. The relationship between the structure and function of the nervous system in health and disease. Topics include organisational principles of the CNS, imaging of the human brain, synaptic function in health and disease, selected topics in pathophysiology of motor and sensory systems (including vision and auditory function), brain ischemia and sleep/sleep disorders. The topics are covered at an advanced level with emphasis on current advances in the fields. An advanced treatment of the human cardiovascular system that provides an integrated framework for understanding the structure, function and regulation of the heart and circulation, and their modification by drugs. Topics include: the energetics and mechanics of the heart, the regulation of heart rhythm and the control of blood pressure and the regulation of flow through the microcirculation. The course is illustrated using examples drawn from current research in the field and from representative disease states. An introduction to the mechanism controlling the production of hormones and how these achieve their effects in regulating body function. The course focuses in particular on the hormone systems controlling growth and metabolism and contrasts the differences between fetal and adult life. It also highlights how defects in endocrine systems are associated with conditions such as obesity and diabetes. Aspects of reproductive biology including: regulation of gonadal function, the menstrual and oestrus cycles, ovulation, spermatogenesis, feto-maternal physiology including placental function, animal reproduction and assisted reproductive technologies.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle Physiology and Pathophysiology of the Brain Cardiovascular Biology Endocrinology of Growth and Metabolism Reproductive Biology Immunology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field. The relationship between the structure and function of the nervous system in health and disease. Topics include organisational principles of the CNS, imaging of the human brain, synaptic function in health and disease, selected topics in pathophysiology of motor and sensory systems (including vision and auditory function), brain ischemia and sleep/sleep disorders. The topics are covered at an advanced level with emphasis on current advances in the fields. An advanced treatment of the human cardiovascular system that provides an integrated framework for understanding the structure, function and regulation of the heart and circulation, and their modification by drugs. Topics include: the energetics and mechanics of the heart, the regulation of heart rhythm and the control of blood pressure and the regulation of flow through the microcirculation. The course is illustrated using examples drawn from current research in the field and from representative disease states. An introduction to the mechanism controlling the production of hormones and how these achieve their effects in regulating body function. The course focuses in particular on the hormone systems controlling growth and metabolism and contrasts the differences between fetal and adult life. It also highlights how defects in endocrine systems are associated with conditions such as obesity and diabetes. Aspects of reproductive biology including: regulation of gonadal function, the menstrual and oestrus cycles, ovulation, spermatogenesis, feto-maternal physiology including placental function, animal reproduction and assisted reproductive technologies. The biology, cellular and molecular events underlying the immune response. The nature and characteristics of antibody-mediated and cell-mediated immunity including antigen recognition and presentation, antibody and T cell receptor structure, immune regulation and cytokines, immunogenetics and histocompatibility. The relationships of the immune system to the activities of pathogenic organisms. Applied immunology including biotechnology, infection, autoimmunity, tumour immunology, transplantation and immunodeficiency.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle Physiology and Pathophysiology of the Brain Cardiovascular Biology Endocrinology of Growth and Metabolism Reproductive Biology Immunology Nutrition, Diet and Gene Interactions

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field. The relationship between the structure and function of the nervous system in health and disease. Topics include organisational principles of the CNS, imaging of the human brain, synaptic function in health and disease, selected topics in pathophysiology of motor and sensory systems (including vision and auditory function), brain ischemia and sleep/sleep disorders. The topics are covered at an advanced level with emphasis on current advances in the fields. An advanced treatment of the human cardiovascular system that provides an integrated framework for understanding the structure, function and regulation of the heart and circulation, and their modification by drugs. Topics include: the energetics and mechanics of the heart, the regulation of heart rhythm and the control of blood pressure and the regulation of flow through the microcirculation. The course is illustrated using examples drawn from current research in the field and from representative disease states. An introduction to the mechanism controlling the production of hormones and how these achieve their effects in regulating body function. The course focuses in particular on the hormone systems controlling growth and metabolism and contrasts the differences between fetal and adult life. It also highlights how defects in endocrine systems are associated with conditions such as obesity and diabetes. Aspects of reproductive biology including: regulation of gonadal function, the menstrual and oestrus cycles, ovulation, spermatogenesis, feto-maternal physiology including placental function, animal reproduction and assisted reproductive technologies. The biology, cellular and molecular events underlying the immune response. The nature and characteristics of antibody-mediated and cell-mediated immunity including antigen recognition and presentation, antibody and T cell receptor structure, immune regulation and cytokines, immunogenetics and histocompatibility. The relationships of the immune system to the activities of pathogenic organisms. Applied immunology including biotechnology, infection, autoimmunity, tumour immunology, transplantation and immunodeficiency. Practical applications of nutrition in protection against, and reduction of symptoms in, chronic disease from a clinical perspective. Both non-communicable diseases (eg, cancer, osteoporosis, auto-immune disease) and communicable disease (eg, whooping cough, influenza) will be considered. Factors regulating appetite and food intake, and the role of genotype and epigenotype will also be studied.
Score: 11.193528 Details | Listing | Web page

University of Auckland - Human Mind and Body Relationships Environmental Threats to Human Health Biology for Biomedical Science: Organ Systems Human Structure and Function Microbiology and Immunology Mechanisms of Disease Introduction to Pharmacology and Toxicology The Physiology of Human Organ Systems Introduction to Neuroscience Molecular Basis of Disease Cancer Biology Principles of Pharmacology Molecular Pharmacology Systematic Pharmacology Principles of Toxicology Neuroscience: Neuropharmacology Molecular Physiology and Neuroscience Biophysics of Nerve and Muscle Physiology and Pathophysiology of the Brain Cardiovascular Biology Endocrinology of Growth and Metabolism Reproductive Biology Immunology Nutrition, Diet and Gene Interactions Bioengineering Neurophysiology

Humans share with other living things the features of physical self-generation and adaptation to the environment. Humans also live in a mental (mind) world and maintain relationships with our perceived environments. Minds and bodies mutually affect one another. This mind/body dance, which is explored in this course, is what gives rise to all of human behaviour from simple daily activities to the highest forms of creativity. Our environment sustains our lives but at times threatens our health. These threats may occur naturally, or arise from damage we have inflicted on the environment. This course considers health impacts of climate change, pollution, lifestyle choices, poverty and affluence, workplace hazards, emerging infectious diseases, and dangers affecting cancer risk. Introduction to human biology with particular emphasis on integrated organ function. The course will deal with: structures and processes associated with the function of the nervous, locomotor, cardiovascular, respiratory, digestive, renal, endocrine, musculoskeletal and reproductive systems. Presents the structure of biological systems with special reference to human biology, from the levels of histology through to gross anatomy. Specific examples of the correlation between structure and function will be considered. An introduction to current techniques for the visualisation of biological structure will be presented. An introduction to the nature and roles of bacteria, viruses, fungi and parasites as the causative agents of human diseases. Topics include: the defence mechanisms of the body, the immune system including autoimmunity and allergy, control of disease by antimicrobials, sterilisation, disinfection and infection control practice. Outlines the basic mechanisms, operating at the molecular, cellular and tissue levels, by which human disease develops. These include genetic factors, cell injury, inflammation, repair, circulatory disturbances, and neoplastic change. These mechanisms are illustrated by descriptions of the pathogenesis of specific diseases that are relevant to the New Zealand situation, or are the focus of current biomedical research. A solid grounding in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response (pharmacodynamics), the fate of drugs within the body (pharmacokinetics), toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development. Selected drug examples will be studied to illustrate key principles of clinical pharmacology. An integrative approach is used to study fundamental physiological processes which enable the body to overcome the challenge of life. Drawing on examples of normal and abnormal function, the course examines the interaction of vital physiological processes, from cellular control mechanisms to multiple organ systems. Topics include: control of fluid and electrolytes, cardiovascular control, energy use, and the delivery of oxygen and metabolites. The impact of neuroscience revolution on our understanding of human physiology and biomedical research is reviewed. Topics include: mechanisms of neurotransmission, learning, memory, sensory perception (vision, hearing, touch and smell) and application of gene therapy for treating neurological diseases. Special emphasis is placed on the integration and control of physiological function by the nervous system. Examples include control of movement and coordination, regulation of reproduction, blood pressure, breathing, appetite, body weight and sexuality. Developmental neuroscience is also considered. Laboratory exercises provide insight into neural structure and function and include application of neuroimaging technologies. An in-depth analysis of the cellular and molecular basis of disease, including the role of environmental and inherited risk factors, as well as mechanisms of response to cell injury and inflammation in the disease process. Models of common diseases such as diabetes, obesity, cancer and infectious agents will be studied. A study of the scientific basis of cancer including: mechanisms underlying the pathogenesis of cancer, carcinogenesis, DNA damage and repair, properties of cancer cells (including abnormalities of growth and cell cycle control), the growth of tumours, the classification and histopathology of cancers, and an introduction to therapeutic strategies. Topics covered are: ADME and pharmacokinetics; therapeutic drug monitoring; drug-drug interactions; pharmacogenetics and pharmacogenomics; drug development and analysis; novel drug delivery, chemotherapy including antibiotics, anticancer and antiviral drugs. Considers the molecular mechanisms of drug action. The cellular and molecular mechanisms of drugs acting at receptors, ion channels, enzymes and intermediate messengers are covered. These concepts are applied through a detailed examination of cell cycle and apoptotic pathways, the molecular basis of drug addiction and the mechanisms of action of common recreational drugs. Considers the modification by drugs of human systems under physiological and pathological conditions. The cellular and molecular mechanisms of drugs as receptors, ion channels, enzymes and intermediate messengers are considered. The modification of drugs on the cardiovascular, gastrointestinal, endocrine, reproductive, respiratory and central nervous systems will be covered. Considers the principles and concepts that result in detrimental effects in animals and humans. It addresses: biochemical pathways and targets in the toxicity of chemicals, the effects at cellular, organ and whole body level, eg, cell death, cancer and hypersensitivity, as well as the basis for cell and organ-selective toxicity. Drugs, occupational and environmental toxicants are discussed. An introduction to the principles and concepts involved in neuropharmacology. The course covers: the anatomy, neurochemistry and pharmacology of the normal and diseased human brain; the biochemical causes of psychiatric and neurological diseases; and the types and mechanisms of action of drugs used to treat brain disorders. The molecular physiology of cellular homeostasis and signaling. This discipline integrates molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience and allied fields. The course considers the characterisation and manipulation of gene expression, and translation to gene therapy treatments for neurological diseases. The lab component focuses on analysis of gene expression and use of recombinant DNA technologies. Practical training includes isolation of RNA, gene cloning, and DNA fingerprinting using the polymerase chain reaction. An advanced treatment of the physiology of excitable cells. Topics include: the biophysical basis of membrane potential, the spread of electrical activation and synaptic transmission, structure, excitation, mechanics and energetics of muscle and functional differences among muscle types. The approach is quantitative with particular emphasis on current advances in the field. The relationship between the structure and function of the nervous system in health and disease. Topics include organisational principles of the CNS, imaging of the human brain, synaptic function in health and disease, selected topics in pathophysiology of motor and sensory systems (including vision and auditory function), brain ischemia and sleep/sleep disorders. The topics are covered at an advanced level with emphasis on current advances in the fields. An advanced treatment of the human cardiovascular system that provides an integrated framework for understanding the structure, function and regulation of the heart and circulation, and their modification by drugs. Topics include: the energetics and mechanics of the heart, the regulation of heart rhythm and the control of blood pressure and the regulation of flow through the microcirculation. The course is illustrated using examples drawn from current research in the field and from representative disease states. An introduction to the mechanism controlling the production of hormones and how these achieve their effects in regulating body function. The course focuses in particular on the hormone systems controlling growth and metabolism and contrasts the differences between fetal and adult life. It also highlights how defects in endocrine systems are associated with conditions such as obesity and diabetes. Aspects of reproductive biology including: regulation of gonadal function, the menstrual and oestrus cycles, ovulation, spermatogenesis, feto-maternal physiology including placental function, animal reproduction and assisted reproductive technologies. The biology, cellular and molecular events underlying the immune response. The nature and characteristics of antibody-mediated and cell-mediated immunity including antigen recognition and presentation, antibody and T cell receptor structure, immune regulation and cytokines, immunogenetics and histocompatibility. The relationships of the immune system to the activities of pathogenic organisms. Applied immunology including biotechnology, infection, autoimmunity, tumour immunology, transplantation and immunodeficiency. Practical applications of nutrition in protection against, and reduction of symptoms in, chronic disease from a clinical perspective. Both non-communicable diseases (eg, cancer, osteoporosis, auto-immune disease) and communicable disease (eg, whooping cough, influenza) will be considered. Factors regulating appetite and food intake, and the role of genotype and epigenotype will also be studied. Advanced molecular physiology of cellular homeostasis and signaling integrating molecular biology, electrophysiology, imaging technologies and other advanced techniques in molecular neuroscience. The use of genetic manipulation treatments for neurological diseases. Design and application of recombinant DNA-based projects for investigating key research questions in neuroscience.
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