| source Lund University (X) |
level |
department Molecular Biology (X) |
Antibiotics are very important compounds. The majority of all known antibiotics are produced by bacteria. Antibiotics were once regarded as miracle drugs. However, they are becoming less effective as bacteria develop resistance against them. The increasing occurrence of micro-organisms that are resistant to multiple antibiotics constitutes a serious threat to human health. The course addresses fundamental questions and problems concerning antibiotics. What is the role of antibiotics in nature? How are they synthesized? What are their modes of action? How can new antibiotics be discovered? How can we attack problems with antibiotic resistant micro-organisms? The course brings a comprehensive understanding of the biology and chemistry of antibiotics. It provides insight into bacterial physiology and also industrial and clinical aspects of antibiotics and about evolution of antibiotic resistance.
Score: 13.596779 Details | Listing | Web page
Score: 13.596779 Details | Listing | Web page
Score: 13.596779 Details | Listing | Web page
Score: 13.596779 Details | Listing | Web page
This course provides an introduction to the practical and theoretical basis of key experimental techniques that are used in molecular biology. Different aspects of genetic engineering (for example, cloning and creating mutations in DNA) in bacteria, yeast, plants and mammalian cells are discussed. Modern techniques such as bioinformatics, DNA microarrays and proteomics are covered. The lectures provide theoretical information, with accompanying tutorials. The practicals allow students to obtain diverse laboratory skills, and to observe in practice selected topics from the lectures. The students will be trained to, in part, independently design and plan molecular biology experiments. The students will be trained to find relevant articles from the primary literature and to critically evaluate published information. Seminars and reports will allow students to practice language and presentation skills.
Score: 13.596779 Details | Listing | Web page
Microbes are the unseen majority on earth. They are found essentially everywhere where there is liquid water and their activities strongly affect all other forms of life. Whatever part of biology you are specialising in, knowledge about microorganisms is valuable. Their importance in e.g. medicine, food industry, biotechnology, and as model organisms in molecular biology is well known, but microbiology has also been strongly developed and renewed. New methods and knowledge make it possible to explore the enormous and to a large extent unexplored resource that the microorganisms constitute and the large impact they have on all biology. This course gives a broad orientation in modern microbiology, designed both for those who will specialise in this subject and for those who will go in other directions. In the course we deal with microbial diversity, function, and physiology, dicuss the significance of molecular biology methods in the study of the microbes, and give an introduction to ecological, medical, and industrial microbiology. The course also gives profound training in practical microbiological work.
Score: 13.596779 Details | Listing | Web page
There is a dramatic development of research methods to visualize biological structures and physiological events. This development runs in parallel with the explosive development in molecular biology and protein biology (genomics and proteomics) - it is important to be able to study where, and under which conditions, the identified genes are expressed and where proteins are localized in cells and organisms. The course focuses on microscopy-based methods used in contemporary research, with emphasis on methods in which fluorescent markers are used to visualize structures and events. The course gives a theoretical background to the most common microscopy methods, different types of biomarkers, and optimization of microscopy samples. The course also contains demonstrations of advanced research microscopes, and a project study where the students prepare and analyze microscopy samples with fluorescent marker(s). The course is suitable for those who consider a career in biomedical sciences in an academic environment or in the industry.
Score: 13.596779 Details | Listing | Web page
This course reviews some of the most exciting topics within yeast and mammalian genetics, cell biology and molecular biology, and looks for possible applications of these topics in biotechnology, medicine, drug development, food technology, etc. This course also provides a view on innovations, patents, start-up companies, and is therefore a good preparation for work in biotech and biomedical industry. The course includes an experimental part on either genetics, cell biology, molecular biology or bioinformatics of bacterial, yeast or mammalian cells, trying to solve applied problems in the lab. For example, (i) you can do a screening for mutants of suicide genes useful for anti-cancer gene therapy, or (ii) analyze the genome of a yeast important in wine industry, etc. This course also contains a large literature project on molecular and cell biology or genetics topics, which also have an applied aspect. For example, you can write a project on: (i) molecular targets for novel antibiotica against multi-resistant microbes, (ii) GMO yeast strains in future food products, (iii) efficient and selective delivery systems in gene therapy, etc. The "classical" exam is replaced by written project reports and their oral presentations. The course concludes with two comprehensive written projects and two oral presentations of the selected theoretical and lab projects.
Score: 13.596779 Details | Listing | Web page
Score: 13.596779 Details | Listing | Web page
The course deals with the structure and function of the genetic material in eukaryotic organisms. Genome organization and mechanisms for gene expression are studied on an advanced level, with a strong connection to the most recent research in molecular genetics. A big attention is put on the methodology and techniques of molecular genetics, which serves as a preparation for postgraduate education and professional work.
Score: 13.596779 Details | Listing | Web page
Bacteria make up the foundation of the biosphere and sustain all life on earth. This course provides insights into how genes are organised and regulated in bacteria and in their viruses. The course comprises molecular biology of genes, proteins, multicomponent protein complexes, and other biomolecules that provide structure and perform the organism s functions. The use of genetic engineering and modern techniques such as transcriptomics, proteomics and sequence analysis are included in the course. The experimental part focus on the most studied bacteria, Bacillus subtilis, Escherichia coli and Streptomyces coelicolor. On completion of the course, the student shall have acquired the intellectual ability and practical skills to work productively in a commercial setting, institute, or university laboratory on different aspects concerning the molecular genetics of bacteria.
Score: 13.596779 Details | Listing | Web page
Score: 13.596779 Details | Listing | Web page
Score: 13.596779 Details | Listing | Web page
On completion of the course, the students shall:
Score: 13.596779 Details | Listing | Web page
On completion of the course, the students shall have acquired the following knowledge and understanding:
Score: 13.596779 Details | Listing | Web page
The course deals with vision and other types of photoreception, olfaction, taste, hearing, equilibrium, mechanoreception, pressure reception, electroreception, magnetoreception and senses for temperature and heat radiation. All senses are studied comparatively across the animal kingdom. A range of methods in physiology, ethology and human psychophysics are taught and used during the course.
Score: 13.596779 Details | Listing | Web page