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Harvard - Cloning, Regeneration, and Reprogramming

This course will focus on the biology of organismal cloning, cellular reprogramming, developmental plasticity, and animal regeneration after injury, including classical experiments in amphibia and planaria. The role that stem cells play in these processes and the genetic and molecular circuitry that underlie developmental potency and reprogramming will be discussed.
Score: 12.412258 Details | Listing | Web page

Harvard - Directed Differentiation of Stem Cells

This practical laboratory course will investigate the fundamental biology of human embryonic stem cells and their remarkable capacity to differentiate into all cells of the body. The underlying developmental pathways that guide embryonic stem cell development into these differentiated cell types will be explored. A chemical biology approach will also be used to probe properties of normal and disease model cells derived from embryonic stem cells.
Score: 12.412258 Details | Listing | Web page

Harvard - Epigenetic Regulation in Development

Cloning of Dolly the sheep suggests that all of our cells have exactly the same genes as a fertilized egg. If this is true, then how is it that each of our cells reads out those genes differently? This course will explain the developmental events that regulate the expression of genes, as well as how this developmental expression is established and maintained.
Score: 12.412258 Details | Listing | Web page

Harvard - Experimental Embryology

This advanced laboratory course will apply experimental approaches and surgical techniques to illustrate critical developmental events during mouse embryogenesis. Particular emphasis will be placed on experiments covering the following topics: fertilization and pre-implantation embryology; reprogramming of adult somatic cells into embryonic stem cells; early organ development; and surgical manipulation of late stage mouse embryos in utero.
Score: 12.412258 Details | Listing | Web page

Harvard - Human Developmental and Regenerative Biology

Fundamental concepts in developmental biology will be presented within the framework of the developing and regenerating mammal. Where possible, lectures will focus on humans.
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Harvard - Introduction to Research

Laboratory research in topics related to the Human Developmental and Regenerative Biology Concentration under the direction of, or approved by, members of the Department of Stem Cell and Regenerative Biology, Principal Faculty of the Harvard Stem Cell Institute, or others with permission. A paper must be submitted to the laboratory sponsor and to the HDRB Concentration Office for review by the Course Director and Head Tutors.
Score: 12.412258 Details | Listing | Web page

Harvard - Laboratory Research for Honors Thesis

For honors candidates writing a thesis in Human Developmental and Regenerative Biology.
Score: 12.412258 Details | Listing | Web page

Harvard - Mechanisms of Epigenetic Reprogramming

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Score: 12.412258 Details | Listing | Web page

Harvard - Mechanisms of Epigenetic Reprogramming

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Score: 12.412258 Details | Listing | Web page

Harvard - Repair and Regeneration in the Mammalian Brain

This course will discuss cellular and molecular mechanisms of regeneration and repair in the mammalian central nervous system (CNS). We will: compare and contrast aspects of neural development with adult neural plasticity; discuss limitations to neuronal regeneration in the mature mammalian CNS following degeneration or injury; examine CNS regeneration approaches directed at overcoming intrinsic limitations; and explore developmental controls and gene manipulation to promote neurogenesis, axonal regeneration, and directed differentiation in the diseased adult brain.
Score: 12.412258 Details | Listing | Web page

Harvard - Understanding Aging: Degeneration, Regeneration, and the Scientific Search for the Fountain of Youth

This lecture and discussion course will explore the fundamental molecular and cellular mechanisms that govern organismal aging and contemporary strategies to delay or reverse this process.
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Harvard - What does Human Disease Teach Us About Mammalian Biology?

Stem cells are the basis for tissue maintenance and repair, thus, are essential elements of normal organ and tissue physiology. Stem cells are also targets for disease processes and through transplantation are important therapeutic agents. This course will allow advanced undergraduates to explore how stem cells and tissue regeneration impact human disease pathogenesis and how stem cells might be exploited to advance new therapies for disease.
Score: 12.412258 Details | Listing | Web page

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