Evolution of development mechanisms with a focus on the genes that regulate segmentation and regionalization of the body plan.
Score: 5.084447 Details | Listing | Web page
Theoretical modeling of complex biological systems; bioinformatics in genetics and development.
Score: 5.084447 Details | Listing | Web page
Biochemical and genetic characterization of proteins that assemble histones onto DNA. Analysis of the relationship of chromatin assembly to DNA replication and gene expression.
Score: 5.084447 Details | Listing | Web page
The Roelink laboratory is interested in the mechanisms of embryonic induction, the phenomenon in which a group of cells changes the developmental fate of neighboring cells via the release of inducers.
Score: 5.084447 Details | Listing | Web page
This course will focus on mechanisms of gene control in vertebrate animals, particularly in the area of vertebrate development. Amphibian egg formation, mesoderm induction, neural induction, and patterning of the nervous system at the molecular level. Control of transcription, post-transcriptional control of gene expression (including control of RNA turnover and RNA localization).
Score: 5.084447 Details | Listing | Web page
Review of current literature and discussion of current research.
Score: 5.084447 Details | Listing | Web page
Molecular and cellular analysis of the immune response. Structure and function of antibodies and antibody genes including antibody-antigen reactions, principles of molecular recognition, recombination and regulation of antibody genes, and the immunoglobulin class switch; B cell differentiation, activation, and tolerance. Structure and function of T cell receptors and T cell receptor genes; antigen processing and presentation, and role of MHC molecules in guiding T cell recognition; T cell activation, development, positive selection, and tolerance. Analysis of T cells, natural killer cells, and tumor surveillance.
Score: 5.084447 Details | Listing | Web page
This is an advanced seminar course which will consider current research questions and experimental approaches in molecular and cellular immunology. Each registrant will present a 30-minute research talk describing the problems they are studying, the approach they are taking, their preliminary data, and technical problems. Other course participants (including basic immunology faculty) will provide criticism and suggestions.
Score: 5.084447 Details | Listing | Web page
Emphasis will be on the treatment or prevention of cancer based on rational approaches derived from recent advances in tumor immunology. The course will examine the application of basic research in immune regulation to more applied studies in animal models and clinical trials. Introductory lectures by instructor followed by student presentations of original literature and lectures by invited speakers engaged in translational and clinical research in tumor immunotherapy.
Score: 5.084447 Details | Listing | Web page
Review of current literature and discussion of original research.
Score: 5.084447 Details | Listing | Web page
Molecular basis of antigen recognition function of T lymphocytes.
Score: 5.084447 Details | Listing | Web page
Molecular biology of T cell receptor genes and their transcription controlling proteins/genes. Programmed cell death during thymocyte differentiation.
Score: 5.084447 Details | Listing | Web page
Molecular and biological basis for development of antigen/MHC repertoire.
Score: 5.084447 Details | Listing | Web page
Molecular and cellular aspects of thymocyte differentiation.
Score: 5.084447 Details | Listing | Web page
Molecular basis of terminal B cell differentiation. Role of transcription factors in B cell activation.
Score: 5.084447 Details | Listing | Web page
Molecular mechanisms involved in the synergistic relationship between V(D)J recombination and lymphocyte development/function.
Score: 5.084447 Details | Listing | Web page
The mechanisms used by viruses to counteract the pressure of the immune system.
Score: 5.084447 Details | Listing | Web page
Innate immunity and innate control of adaptive immunity.
Score: 5.084447 Details | Listing | Web page
Role of innate host responses in defense against intracellular bacterial pathogens.
Score: 5.084447 Details | Listing | Web page
Comprehensive survey of current state of knowledge in molecular, cellular, developmental, integrative and behavioral aspects of neurobiology.
Score: 5.084447 Details | Listing | Web page
Physical-chemical basis of membrane potentials, electrotonus, action potential generation and propagation, synaptic transmission, sensory receptor function, and volume conductor potentials. Also listed as Neuroscience C261.
Score: 5.084447 Details | Listing | Web page
Advanced coverage of current research problems in systems-level neuroscience, and experimental and computational techniques used for these studies. Also listed as Neuroscience C262.
Score: 5.084447 Details | Listing | Web page
Advanced level coverage of current research problems in the embryonic and post-embryonic development of invertebrate and vertebrate nervous systems. Also listed as Neuroscience C263.
Score: 5.084447 Details | Listing | Web page
Review of current literature and discussion of original research.
Score: 5.084447 Details | Listing | Web page
Molecular and cellular studies of nerve growth, axon guidance, synaptic formation, and synaptic plasticity using electrophysiological and optical imaging techniques.
Score: 5.084447 Details | Listing | Web page
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