BIOL-354 is intended for junior and senior Biology majors who have taken Gateway to Neurobiology. This course will examine how neurons communicate with each other through synaptic connections. It will begin with some basic information about human neuroanatomy, providing the groundwork for understanding how disruptions in specific systems result in specific outcomes. We will then examine the basic cell biology of synaptic transmission, focusing on the different types of neurotransmitters and their receptors. We will explore the molecular regulation of these systems, the effects of therapeutic and non-therapeutic drugs, and the transfer of information from outside the cell to inside.
Score: 5.473717 Details | Listing | Web page
Credits: 4
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
The class combines basic knowledge of thermodynamics/statistical physics, nonlinear dynamics and biology to highlight physical processes that govern the dynamics of biological systems. The class will concentrate on dynamical aspects emerging on different temporal and spatial scales, Brownian motion and diffusion, thermodynamics of biological processes, protein folding, generation of membrane potentials, spatio-temporal pattern generation in neural networks.
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
A study of the molecular and biochemical bases for cell structure and functions, control of gene expression, membrane organization, organelle assembly and specialized functions, structure/function dynamics of the cytoskeleton, interactions with the extracellular matrix, mechanisms of signal transduction, solute translocation, endocytosis and exocytosis, growth control, and oncogenesis will be covered. The laboratory is designed to illustrate concepts presented in lecture and to introduce students to the scientific method and experimental design. Prerequisites BIOL-151 and -152, or by special permission. Three lecture hours and one three-hour laboratory. Fall.
Score: 5.473717 Details | Listing | Web page
This course will explore the diversity of the microbe world, including bacteria, archaea, fungi, protists, and viruses. We will examine the range of interactions observed between microbes and their environments, with a particular emphasis on human-microbe associations. The four major sections of the course will focus on: (1) the evolution of microbial diversity; (2) unique aspects of microbe biochemistry relevant to microbial lifestyles; (3) infectious diseases of animals and plants; and (4) the role of microbes in the environment. Three double-periods per week will emphasize discussion of a diversity of reading material and laboratory investigations designed and conducted by students. Prerequisites: BIOL-103 and -104.
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
What processes shape genetic variation and genetic diversity and what patterns do we expect in genetic systems? The answer to this question will be sought in a broad examination of genetic principles that operate during the course of evolutionary change. Topics covered include genetic drift, inbreeding, effective population size, gene flow, natural selection, quantitative genetics, and molecular evolution. This course stresses computer simulation as a learning tool and seeks to illuminate connections among Hardy-Weinberg systems, continuous trait genetics, and molecular genetics. The laboratory sessions will cover practical applications including genetic hypothesis testing, computer simulations, and forensic DNA typing. Prerequisite: BIOL-152.
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
Parasitic diseases include some of the most common and deadly infections in the world. This course will introduce students to the major parasitic diseases of man. We will emphasize the interesting and unique life styles of parasitic organisms, transmission of these diseases, development of chemotherapeutics and vaccines to treat them, and their impact on global health. Diseases covered include malaria, giardiasis, sleeping sickness, schistosomiasis and ascariasis.
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
This laboratory is designed to supplement the material learned in BIOL-373. Students will study developmental anatomy of vertebrate embryos at different stages of development and will perform classical embryology experiments discussed in the lecture portion of the course. A variety of organisms will be used, including frogs, salamanders, chicks, sea urchins, sponges, fruit flies and etc. Three hour laboratory to be taken with BIOL-373.
Score: 5.473717 Details | Listing | Web page
This course will examine ecological and evolutionary themes in plant-animal interactions, focusing on pollination biology, fruit and seed dispersal, and herbivory. Suitable for advanced undergraduates and graduate students. Course will consist of lectures, presentation and discussion of the primary literature, and some laboratory and field projects. Limited to 10 students.
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
Credits: 3
Score: 5.473717 Details | Listing | Web page
Ecology seeks to understand how organisms interact with both their abiotic (nonliving) and biotic environments, and how such interactions affect species distribution and abundance as well as the structure of ecological communities. To quantify these relationships and understand the underlying causal mechanisms, ecologists utilize both observational and experimental studies. Understanding how to test hypotheses and design experiments is fundamental to all branches of science, but ecology and other field sciences face unique challenges. This course will help students understand the critical importance of appropriate experimental design, and methods of data analysis when testing hypotheses in environmental biology. The course will be oriented around hands-on field and laboratory experiences with experimental design, data collection, data analysis techniques, null model formulation and hypothesis testing.
Score: 5.473717 Details | Listing | Web page
Credits: 3 (lecture only), 4 (lecture and lab)
Score: 5.473717 Details | Listing | Web page
This course is an in-depth look at the central dogma of molecular biology. Emphasis will be placed on analysis of whole genomes and the impact of genome sequencing projects on biologists. Mechanisms of DNA replication, repair, and division as well as mechanisms of gene expression in both prokaryotes and eukaryotes will also be discussed. Experimental approaches to issues in molecular biology will be emphasized using analysis of primary literature in addition to textbook readings. Class meets 3 times/week. Lab/recitation meets once/week and will include computer-based labs, traditional labs and journal club formats. Prerequisites: BIOL-151 and -152. Spring.
Score: 5.473717 Details | Listing | Web page
The course focuses on the molecular mechanisms of signal transduction. In particular, we will review structure-function relationships of G protein-coupled receptors (GPCRs) and the proteins involved in the multitude of pathways through which they signal. We will also review signaling through receptors with associated tyrosine kinase activity and regulation of gene expression by intracellular nuclear hormone receptors (NHRs). Particular attention will be given to bibliographic searches and to the direct study of the pertinent literature. Each theoretical lecture will be followed by one hour of molecular modeling laboratory, in which we will visualize and analyze the three-dimensional structures of the studied signal transduction components. We will also generate homology models, analyze binding interfaces, and conduct computational ligand-protein and protein-protein docking experiments.
Score: 5.473717 Details | Listing | Web page
Credits: 1
Score: 5.473717 Details | Listing | Web page
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