Prereq: 540.311 or 540.313, 540.301 and 540.306 This course guides the student through the contrasting aspects of product design and of process design. Product design concerns the recognition of customer needs, the creation of suitable specifications, and the selection of best products to fulfill the needs. Process design concerns the quantitative description of processes, which serve to produce many commodity chemicals, the estimation of process profitability, and the potential for profitability improvement through incremental changes in the process. Students work in small teams to complete a major project demonstrating their understanding of and proficiency in the primary objectives of the course. Students report several times both orally and in writing on their accomplishments.
Score: 6.7114224 Details | Listing | Web page
Prereq: 540.203 or 030.301 or permission from instructor. The prediction of protein structure from the amino acid sequence has been a grand challenge problem for over fifty years. With recent progress in research, it is now possible to blindly predict many protein structures and even to design new structures from scratch. This class will introduce the fundamental concepts in protein structure, biophysics, optimization and informatics that have enabled the breakthroughs in computational structure prediction and design. Problems covered will include protein folding and docking, design of ligand-binding sites, design of turns and folds, design of protein interfaces. Students will learn to use molecular visualization tools and write programs with the Rosetta protein structure software suite, including a computational project. Programming experience is helpful but not required. Meets with 540.614
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Prereqs: 020.305 or 580.221 One of the most promising strategies for successfully designing complex biomolecular fuinctions is to exploit nature's principles of evolution. This course provides an overview of the basics of molecular evolution as well as its experimental implementation. Current research problems in evolution-based biomolecular engineering will be used to illustrate principles in the design of biomolecules (i.e. protein engineering, RNA/DNA engineering), genetic circuits and complex biological systems including cells. (Will meet with EN.540.637)
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Prereqs: 540.311 or 540.313 or permission of instructor Micro/Nanotechnology is the field of fabrication, characterization and manipulation of extremely small objects (dimensions on the micron to nanometer length scale). Microscale objects, because of their small size are expected to be at the frontier of technological innovation for the next decade. This course will include a description of the materials used in microtechnology, methods employed to fabricate nanoscale objects, techniques involved in characterizing and exploiting the properties of small structures, and examples of how this technology is revolutionizing the areas of Electronics & Medicine. Same course as 540.640
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Registration with permission of instructor only.
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Great ideas in Behavioral Biology. Discussion of classic and cutting edge articles in the original literature. Student presentations and reaction papers. Capstone course for senior Behavioral Biology majors.
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