Prokaryotic microbial physiology will be discussed primarily from a biochemical standpoint with emphasis on mechanism. Topics will vary from year to year but will include the following themes: Central metabolism, bioenergetics, biosynthesis, regulation, differentiation, prokaryotic structure-function relationships.
Score: 5.4045453 Details | Listing | Web page
Replication cycle and gene regulation of HIV. Molecular approaches to therapy and vaccines. Three hours of lecture.
Score: 5.4045453 Details | Listing | Web page
This course covers basic processes of transformation and tumor formation in a two-part format. The first section is focused on molecular and cellular mechanisms of carcinogenesis. The second section discusses tumor pathology and metastasis. Open to upper-division students only.
Score: 5.4045453 Details | Listing | Web page
This course will focus on large-scale analysis of post-genomics biological systems. Students will be introduced to methods for analyzing changes in gene expression, identifying protein-protein interactions, screening for pathway inhibitors, characterizing multiprotein complexes, and probing protein localization and function.
Score: 5.4045453 Details | Listing | Web page
Biological macromolecules and supramolecular complexes as well as organelles, and small cells are being examined in three-dimensions by modern electron cryomicroscopy and image reconstruction techniques. The basic principles of transmission electron microscopy and 3D image reconstruction are discussed.
Score: 5.4045453 Details | Listing | Web page
(Cross-listed with CHEM 166; conjoined with BGGN 256, BIOM 266, and CHEM 266.) This course will investigate approaches to study the impact of environmental toxicants on human health. Other modern approaches that are being implemeneted to detect and remediate environmental toxicants will also be examined. Graduate students will be required to complete an additional paper and/or exam beyond that expected of undergraduate students.
Score: 5.4045453 Details | Listing | Web page
Students will isolate bacterial viruses or other organisms from the environment and characterize them by methods including electron microscopy and nucleic acid analysis. The genomic DNA will be purified, and sent for sequencing. Students may not enroll in or receive credit for both BIMM 171A and BIEB 123 or BIMM 171A and BIMM 101.
Score: 5.4045453 Details | Listing | Web page
Students will characterize the genomic sequence of the organisms isolated in BIMM 171A and use molecular and computational tools to resolve ambiguities and close gaps. They will then annotate the DNA sequence to identify protein and RNA coding regions. Students may not enroll in or receive credit for both BIMM 171B and BIEB 123 or BIMM 171B and BIMM 101.
Score: 5.4045453 Details | Listing | Web page
Computational methods will be used to characterize the annotated genome sequence produced in BIMM 171A-B to study the evolution of genes and their products. Various mechanisms shaping genome evolution will be discussed and the genome evaluated for evidence of these processes. Students may not enroll or receive credit for both BIMM 171C and BIEB 123 or BIMM 171C and BIMM 101.
Score: 5.4045453 Details | Listing | Web page
This course covers the analysis of nucleic acid and protein sequences, with an emphasis on the application of algorithms to biological problems. Topics include sequence alignments, database searching, comparative genomics, and phylogenetic and clustering analyses. Pairwise alignment, multiple alignment, DNA sequencing, scoring functions, fast database search, comparative genomics, clustering, phylogenetic trees, gene finding/DNA statistics. This course open to bioinformatics majors only.
Score: 5.4045453 Details | Listing | Web page
This course provides an introduction to the features of biological data, how that data are organized efficiently in databases, and how existing data resources can be utilized to solve a variety of biological problems. Object-oriented databases, data modeling and description, survey of current biological database with respect to above, implementation of database focused on a biological topic. This course open to bioinformatics majors only.
Score: 5.4045453 Details | Listing | Web page
This advanced course covers the application of machine learning and modeling techniques to biological systems. Topics include gene structure, recognition of DNA and protein sequence patterns, classification, and protein structure prediction. Pattern discovery, hidden Markov models/support vector machines/ neural network/profiles, protein structure prediction, functional characterization of proteins, functional genomics/proteomics, metabolic pathways/gene networks. This course open to bioinformatics majors only.
Score: 5.4045453 Details | Listing | Web page
This course introduces the concepts of physiological regulation, controlled and integrated by the nervous and endocrine systems. It then examines the muscular, cardiovascular, and renal systems in detail and considers their control through the interaction of nervous activity and hormones. Three hours of lecture and one hour of discussion.
Score: 5.4045453 Details | Listing | Web page
This course completes a survey of organ systems begun in BIPN 100 by considering the respiratory and gastrointestinal systems. Consideration is given to interactions of these systems in weight and temperature regulation, exercise physiology, stress, and pregnancy and reproduction. Three hours of lecture and one hour of section per week.
Score: 5.4045453 Details | Listing | Web page
Experiments are performed on membrane physiology; nerve muscle function; cardiovascular physiology; respiratory, gastrointestinal and renal physiology. Subjects include experimental animals and humans.
Score: 5.4045453 Details | Listing | Web page
This course examines the physiological adaptation of animals, invertebrates and vertebrates, to their particular environmental and behavioral niches. Structural, functional, and molecular adaptaions of the basic organ systems are discussed.
Score: 5.4045453 Details | Listing | Web page
Course addresses the human body’s response to exercise, addressing energy metabolism and the effects of both acute and chronic exercise on function in several important organ systems. Designing training regimes and the role of exercise in health will be considered.
Score: 5.4045453 Details | Listing | Web page
Course will offer in-depth instruction to human anatomy and diseases from the conceptual framework of organ systems. Central nervous system, cardiovascular system, and gastrointestinal system will be discussed in terms of normal anatomy, pathology, and relevant scientific frontiers.
Score: 5.4045453 Details | Listing | Web page
This course covers the biophysics of the resting and active membranes of nerve cells. It also covers the mechanisms of sensory transduction and neuromodulation, as well as the molecular basis of nerve cell function.
Score: 5.4045453 Details | Listing | Web page
This course covers integrated networks of nerve cells, including simple circuits like those involved in spinal reflexes. We will study how information and motor output is integrated and processed in the brain. We will also discuss higher-level neural processing.
Score: 5.4045453 Details | Listing | Web page
Molecular basis of neuronal cell fate determination, axon pathfinding, synaptogenesis experience-based refinement of connections, and learning in the brain will be examined.
Score: 5.4045453 Details | Listing | Web page
Basic principles of nerve and muscle physiology will be taught through weekly exercises and individual projects. One hour of lecture and nine hours of laboratory each week.
Score: 5.4045453 Details | Listing | Web page
An exploration of computational brain models, including biophysical models of single neurons, small neural circuits, and larger scale network models.
Score: 5.4045453 Details | Listing | Web page
Cellular and molecular mechanisms that underlie learning and memory. Synapse formation and synaptic plasticity, neurotransmitter systems and their receptors, mechanisms of synaptic modification, and effect of experience on neuronal connectivity, and gene expression.
Score: 5.4045453 Details | Listing | Web page
Course will be taught from a research perspective, highlighting the biological pathways impacted by different neurological diseases. Each disease covered will be used to illustrate a key molecular/cellular pathway involved in proper neurological function.
Score: 5.4045453 Details | Listing | Web page
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