This course provides detailed coverage of the cellular and molecular basis of cellular transformation and oncogenesis. There will be extensive discussion on the role of oncogenes and their cellular counterparts. The course also provides in-depth analysis of intracellular signal transduction mechanisms.
Score: 5.4045453 Details | Listing | Web page
The course will introduce students to a variety of signal transduction pathways and their function in the regulation of cellular processes. Special emphasis will be given to signaling cascades regulating immunological responses and alterations of signaling pathways during oncogenesis. (W)
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Research papers from all aspects of stem cell biology will be read, presented, and discussed. Papers will range from landmark to current studies, spanning many developmental organisms and cell types. Students will present one paper, provide relevant background, and lead discussions.
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This course covers the molecular and cellular events in the humoral and cellular response to antigen, transplantation biology, the structure and function of the major histocompatibility gene complex, the T-cell receptor, lymphokines, and the induction of immunological tolerance. It serves as the second course in a two-part sequence. May be taken by undergraduates who have taken Part 1 (BICD 140) and by graduate students (S/U grades only.) (Quarter offered varies and course is not offered every year.)
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This course covers recent advances in cell biology, biochemistry, immunology, and virology as they relate to cancer cells and their interaction with the host. Cancer research specialists from outside will be brought in to discuss the most recent evidence and interpretations in key areas of cancer research. This course meets two hours per week for lecture and discussion. It will be at an advanced graduate level but open to a limited number of seniors (with permission of instructor) on a P/NP basis. (S/U grades only) (Quarter offered varies, and course is not offered every year.)
Score: 5.4045453 Details | Listing | Web page
To introduce students with structural and functional properties of microorganisms and with the role of microbes in the world. Course will emphasize the integrative aspects of microbiology. First course in series.
Score: 5.4045453 Details | Listing | Web page
To introduce students with structural and functional properties of microorganisms and with the role of microbes in the world. Course will emphasize the integrative aspects of microbiology. Second course in series.
Score: 5.4045453 Details | Listing | Web page
Students read classic and modern papers that form the basis of the undergraduate lectures (BIPN 240), which they are encouraged to attend. These papers are presented by the students at weekly discussion sessions.
Score: 5.4045453 Details | Listing | Web page
Students read classic and modern papers that form the basis of the undergraduate lectures (BIPN 142), which they are encouraged to attend. These papers are presented by the students at weekly discussion sessions.
Score: 5.4045453 Details | Listing | Web page
Ways in which neurons are assembled into circuits to achieve perception and patterned movement.
Score: 5.4045453 Details | Listing | Web page
Students read classic and modern papers that form the basis of the undergraduate lectures (BIPN 146), which they are encouraged to attend. Students present these papers at weekly discussion sessions. The focus of 246A is cellular neuronal properties and the focus of 246B is properties of neuronal systems.
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These courses are designed for graduate students in the neurosciences and other departments that are part of the interdisciplinary program (i.e., Biology, Cog. SCI). These courses have been designed to cover as much basic neuroscience as possible in three quarters of study. They will combine two three-hour meetings each week with a 1.5 hour lecture and a 1.5 hour discussion of papers. These are required courses for all first-year neurosciences graduate students.
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The first section of this course consists of a review of fundamental concepts in molecular biology together with an in-depth analysis of molecular biological topics of medical importance. The second section covers the structure, genetics, and multiplication of animal viruses, with particular emphasis on the DNA and RNA tumor viruses. Other subjects discussed include viral persistence, latency, and approaches to viral chemotherapy. Three hours of lecture.
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Human genetics, with emphasis on basic principles. Topics covered include chromosome abnormalities, the mechanisms of dominant and recessive diseases, pedigree analysis, ascertainment of linkage, the interaction of genotype with diseases. Mechanisms of maintaining genetic diversity in human populations will be discussed along with recent approaches to genetic counseling and intervention.
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Graduate students will explore topics in specialized areas of immunochemistry and cellular immunology, antigenic and molecular structure of immunoglobulin molecules; antigenantibody interactions; cellular events in the humoral and cellular immune responses; translation immunology.
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This course is a survey covering current subjects in membrane biology relevant to medicine. Subjects are: 1) membrane isolation, composition, and structure; 2) consequences of membrane fluidity (mode of action of anesthetics, intercellular communication, eso- and endo-cytosis biogenesis); 3) sensory perception and response (chemo- and energy reception, cellular neurophysiology, muscle; physiology); 4) regulation of membrane function (hormone reception, intercellular adhesion, neoplastic transformation).
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Introduction to the nonlinear dynamics of neurons and simple neural systems through nonlinear dynamics, bifurcation theory, and chaotic motions. The dynamics of single cells is considered at different levels of abstraction, e.g., biophysical and âreducedâ models for analysis of regularly spiking and bursting cells, their dynamical properties, and their representation in phase space. Laboratory exercises will accompany the lectures.
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Experiments that emphasize biophysical principles through hands-on experience, with an emphasis on the blending of physical measurements with a clearly identified biological problem. Exercises include the use of optical tweezers to measure viscous forces at the level of cellular organelles, the characterization of sensorimotor control in the fly during visually guided flight, and the use of microscopic imaging techniques to characterize cell motility and organelle transport. Includes instruction in LabView. Students are encouraged to attend the Phys. 173 undergraduate lectures.
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An intensive course to introduce the mathematical concepts and techniques used in modern neurobiology. Intended for beginning graduate students in the neurosciences, but is also available to advanced undergraduates, with the consent of the instructor.
Score: 5.4045453 Details | Listing | Web page
Advanced laboratory and/or field experience in contemporary biological methodology. Open only to students enrolled in the integrated Bachelor’s/Master’s Degree Program.
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Group and individual discussion of research activities and of current literature.
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An introduction to contemporary laboratory techniques and research interests through independent, original projects under the direction of individual faculty members.
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(F,W,S)
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This course involves participation in upper-division undergraduate teaching at the level of assuming responsibility for recitation sections or laboratories under the supervision of the responsible faculty member. Some experience in lecturing to upper-division classes will occasionally be provided. (S/U grades only.) (F,W,S)
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Weekly presentations and discussions pertaining to research results reported in recently published literature.
Score: 5.4045453 Details | Listing | Web page
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