A detailed discussion of protein chemistry, ranging from the structure, thermodynamics, and folding of proteins to the relationship between structure and function, and encompassing the methods used to determine such information.
Score: 5.5456305 Details | Listing | Web page
A variety of contemporary problems in biochemistry and molecular biology are investigated in a detailed manner. Lecture: 3-1/2 hours.
Score: 5.5456305 Details | Listing | Web page
A study of enzyme kinetics, mechanisms, and factors involved in enzymic catalysis. Lecture: 3-1/2 hours. Offered in alternate academic years.
Score: 5.5456305 Details | Listing | Web page
The role played by transition metals in biological systems is discussed through application of the principles of coordination chemistry and inorganic spectroscopy. Topics include metalloproteins involved in oxygen binding, iron storage, biological redox reactions, and nitrogen fixation, as well as metal complexes of nucleic acids. Lecture: 4 hours. Prerequisite(s): courses 151A/L, 163A; and Biochemistry and Molecular Biology 100A.
Score: 5.5456305 Details | Listing | Web page
A discussion of the application of selected topics in biophysical chemistry to contemporary problems in biochemistry and molecular biology. Lecture: 3-1/2 hours. Offered in alternate academic years.
Score: 5.5456305 Details | Listing | Web page
Basic principles and methods of the kinetic study of reaction mechanisms are covered, including linear free energy relationships. Theories are examined concerning how reactions choose a mechanism.
Score: 5.5456305 Details | Listing | Web page
Focuses on solid phase synthetic methods as applied to synthesis of compound libraries. Explores advances in laboratory automation, library synthesis, encoding and decoding schemes, and computational approaches to library design and virtual screening. Enrollment restricted to seniors and graduate students.
Score: 5.5456305 Details | Listing | Web page
Determination of 2-D and 3-D structure and functionality of organic molecules from spectroscopic properties, including nuclear magnetic resonance, infrared, ultraviolet-visible and mass spectroscopy.
Score: 5.5456305 Details | Listing | Web page
An advanced study designed to provide the background and insight to enable the student to compare and contrast new reagents and reactions with existing methods. Prerequisite(s): course 143.
Score: 5.5456305 Details | Listing | Web page
An advanced study on the use of chemoselectivity, regioselectivity, and stereoselectivity in organic transformations. Strategic planning in approaching the synthesis of complex molecules focuses primarily on retrosynthetic analysis and stereochemical control. Prerequisite(s): course 240E.
Score: 5.5456305 Details | Listing | Web page
Chemistry of amino acids and secondary structure of amino acid polymers (peptides and proteins) discussed. Special emphasis placed on structure and function of the distinct amino acid side chain functionality as it contributes to structure and function.
Score: 5.5456305 Details | Listing | Web page
A graduate course covering advanced topics in organic chemistry. Topics vary from year to year.
Score: 5.5456305 Details | Listing | Web page
Qualitative molecular orbital concepts, especially concerning aromaticity, orbital symmetry, and perturbation theory, and their application toward interpretation of reactivity and mechanism. Lecture: 3-1/2 hours. Prerequisite(s): courses 273 and 240A. Offered in alternate academic years. May be repeated for credit.
Score: 5.5456305 Details | Listing | Web page
A survey of organic natural products from marine sources. Organic chemical structural families unique to marine organisms are outlined. Pathways of their synthesis and interconversions; their role in the marine environment; approaches to their analysis; the distribution of organics in seawater. Lecture: 3-1/2 hours. Prerequisite(s): courses 108B/M or 112C/N. Offered in alternate academic years. May be repeated for credit.
Score: 5.5456305 Details | Listing | Web page
An introduction to digital computers and their applications in chemistry. Includes Monte Carlo, artificial intelligence, pattern recognition, modeling, simulation, and optimization problem-solving methods. Applications to include structural analysis, spectroscopy, organic synthesis, and kinetics. Lecture: 3-1/2 hours; laboratory: 1-1/2 hours. Offered in alternate academic years. May be repeated for credit.
Score: 5.5456305 Details | Listing | Web page
An introduction to organoborane chemistry and its applications to synthetic organic chemistry, including principles, synthetic methods, reaction mechanisms, and asymmetric synthesis. A variety of topics including allylboration, boron-enolates, and asymmetric reductions are discussed. Enrollment restricted to seniors and graduate students. Offered in alternate academic years. May be repeated for credit.
Score: 5.5456305 Details | Listing | Web page
Advanced study of synthesis and reactions of heterocyclic organic compounds; particular emphasis on structures with important medicinal value from natural products or pharmaceutical research. Prerequisite(s): course 143 or approval of instructor.
Score: 5.5456305 Details | Listing | Web page
Covers a range of topics including radical stabilization, rates of fundamental radical reactions, methods of radical generation, synthetic applications of free radicals, persistent radicals, and some aspects of free radicals in biology. Prerequisite(s): course 143 or permission of instructor.
Score: 5.5456305 Details | Listing | Web page
Kinetic approach to selected topics in mechanistic chemistry with emphasis on structure-reactivity relationships in organic as well as inorganic and biochemical systems. Discussion of significance and treatment of kinetic data illustrated with examples from various branches of chemistry. Prerequisite(s): permission of instructor.
Score: 5.5456305 Details | Listing | Web page
Recommended for students interested in careers in the biopharmaceutical industry. Focuses on recombinant DNA technology and the drug-development process, including discovery research; preclinical testing; clinical trials; and regulatory review, as well as manufacturing and production considerations. Students may not receive credit for this course and Biomolecular Engineering 155. (Also offered as Biomolecular Engineering 255. Students cannot receive credit for both courses.) Enrollment restricted to graduate students. Enrollment limited to 10.
Score: 5.5456305 Details | Listing | Web page
Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry. Prerequisite(s): courses 151A/L and 146B or graduate standing.
Score: 5.5456305 Details | Listing | Web page
Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry. Prerequisite(s): courses 151A/L and 146B or graduate standing.
Score: 5.5456305 Details | Listing | Web page
Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry. Prerequisite(s): courses 151A/L and 146B or graduate standing.
Score: 5.5456305 Details | Listing | Web page
Course in chemical crystallography focuses on the needs of small-molecule, single-crystal diffraction studies. Includes diffraction theory, space-group analysis, data collection, structure solution, and refinement. Practical component: use of diffraction equipment and solution/refinement software. Enrollment restricted to graduate students and seniors who have taken courses 151A, 151L, and 163A.
Score: 5.5456305 Details | Listing | Web page
The basic theory of time dependent processes is covered at an advanced level. The interaction of electromagnetic radiation and matter is described using both semiclassical and quantum field formulations. A variety of modern spectroscopic techniques are discussed both in terms of the basic processes and their use in the elucidation of chemical structure and dynamics. Prerequisite(s): course 163A. Offered in alternate academic years.
Score: 5.5456305 Details | Listing | Web page
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